Table 3.
Statistics of the pathway database comparison
| Number of (percentage of union) | |||||
|---|---|---|---|---|---|
| Genes | EC numbers | Metabolites | Reactions | Reactions (ignoring e - , H + , H 2 O) | |
| union | 3858 | 1410 | 4679 | 7758 | 6968 |
| consensus | 510 (13%) | 259 (18%) | 400 (9%) | 101 (1%) | 199 (3%) |
| majority score | 1636 (42%) | 709 (50%) | 967 (21%) | 732 (9%) | 1004 (14%) |
| Database | Unique per database (percentage of union) | ||||
| BiGG | 45 (1%) | 48 (3%) | 528 (11%) | 1441 (19%) | 1250 (18%) |
| EHMN | 128 (3%) | 82 (6%) | 1184 (25%) | 2120 (27%) | 1832 (26%) |
| HumanCyc | 759 (20%) | 294 (21%) | 739 (16%) | 1032 (13%) | 905 (13%) |
| KEGG | 63 (2%) | 13 (1%) | 282 (6%) | 414 (5%) | 348 (5%) |
| Reactome | 144 (4%) | 11 (1%) | 406 (9%) | 601 (8%) | 539 (8%) |
| Total | 1139 (30%) | 448 (32%) | 3139 (67%) | 5608 (72%) | 4874 (70%) |
Genes: Entrez Gene IDs, including genes encoding for a component of a protein complex as separate entities. EC numbers: only fully specified EC numbers. Metabolites: if two metabolites of one database both match the same metabolite in another database this is counted as one match. The first 'Reactions' column: all reactions are considered. The second 'Reactions' column: reactions were not required to match on e-, H+ and/or H2O.