Figure 2.
Body and tissue weights of iARKO and control mice treated with vehicle (V) or tamoxifen (TM). (A) Body weights (mean ± SEM) of iARKO and control mice (ARflox/y) were measured before treatment (day 35, 42 and 49) and one day after treatment (day 55) with V or TM (3 mg/day for five consecutive days). (B) Tissue weights (mean + SEM) for kidney (K), testis (T), epididymis (E), seminal vesicle (SV), anterior prostate (AP) and ventral prostate (VP) measured one day after treatment (day 55). Control + V: control mice treated with vehicle (n = 7); control + TM: control mice treated with TM (n = 8); iARKO+V: iARKO mice treated with vehicle (n = 5); iARKO+TM: iARKO mice treated with TM (n = 5). ANOVA supplemented with a Fisher LSD test was used to compare body and tissue weights of different treatment groups. Values that differ significantly (p ≤ 0.05) are indicated by different lowercase letters (a–c).