Table 1.
Comparison of Self-Reported Acetaminophen and Ibuprofen Use With Detection of Acetaminophen and/or Ibuprofen Metabolites in Urine Specimens of Belfast and Chicago Participants, by Gender and Age, International Study of Macro-/Micro-Nutrients and Blood Pressure, 1996–1999
| Concordance of Urinary and Self-Report Data | Location, Gender, and Age Group, years |
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| Belfast, Northern Ireland (n = 216) |
Chicago, Illinois (n = 280) |
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| Men (n = 125) |
Women (n = 91) |
Subtotal (n = 216) |
Men (n = 138) |
Women (n = 142) |
Subtotal (n = 280) |
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| 40–49 (n = 59) |
50–59 (n = 66) |
40–49 (n = 59) |
50–59 (n = 32) |
40–49 (n = 59) |
50–59 (n = 66) |
50–59 (n = 32) |
50–59 (n = 32) |
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| % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | % | 95% CI | |
| Concordancea at both visits | 89.8 | 82.1, 97.5 | 92.4 | 86.0, 98.8 | 74.6 | 63.4, 85.6 | 71.9 | 56.2, 87.4 | 83.8 | 78.9, 88.7 | 84.7 | 76.4, 93.0 | 80.3 | 70.7, 89.8 | 80.0 | 70.6, 89.3 | 79.2 | 69.7, 88.5 | 81.1 | 76.5, 85.7 |
| Underreportingb | ||||||||||||||||||||
| At 1 visit onlyc | 10.2 | 2.5, 17.8 | 7.6 | 1.2, 13.9 | 23.7 | 12.8, 34.5 | 15.6 | 3.0, 28.2 | 13.9 | 9.3, 18.5 | 6.9 | 1.1, 12.8 | 10.6 | 3.2, 18.0 | 11.4 | 4.0, 18.8 | 13.9 | 5.9, 21.8 | 10.7 | 7.1, 14.3 |
| At both visits | 0 | 0, 0 | 0 | 0, 0 | 1.7 | 0, 5.0 | 6.3 | 0, 14.6 | 1.4 | 0, 2.9 | 4.2 | 0, 8.8 | 6.1 | 0.3, 11.8 | 8.6 | 2.0, 15.1 | 5.6 | 0.3, 10.8 | 6.1 | 3.3, 8.9 |
| Subtotal | 10.2 | 2.5, 17.8 | 7.6 | 1.2, 13.9 | 25.4 | 14.3, 36.5 | 21.9 | 7.6, 36.1 | 15.3 | 10.5, 20.1 | 11.1 | 3.9, 18.3 | 16.7 | 7.7, 25.6 | 20.0 | 10.6, 29.3 | 19.4 | 10.3, 28.5 | 16.8 | 12.4, 21.2 |
| Underdetectiond | ||||||||||||||||||||
| At 1 visit onlyc | 0 | 0, 0 | 0 | 0, 0 | 0 | 0, 0 | 6.3 | 0, 14.6 | 0.9 | 0, 2.2 | 4.2 | 0, 8.8 | 0 | 0, 0 | 0 | 0, 0 | 0 | 0, 0 | 1.1 | 0, 2.3 |
| At both visits | 0 | 0, 0 | 0 | 0, 0 | 0 | 0, 0 | 0 | 0, 0 | 0 | 0 | 0 | 0, 0 | 1.5 | 0, 4.5 | 0 | 0, 0 | 0 | 0, 0 | 0.4 | 0, 1.1 |
| Subtotal | 0 | 0, 0 | 0 | 0, 0 | 0 | 0, 0 | 6.3 | 0, 14.6 | 0.9 | 0, 2.2 | 4.2 | 0, 8.8 | 1.5 | 0, 4.5 | 0 | 0, 0 | 0 | 0, 0 | 1.4 | 0, 2.8 |
| Mixed findingse | 0 | 0, 0 | 0 | 0, 0 | 0 | 0, 0 | 0 | 0, 0 | 0 | 0 | 0 | 0, 0 | 1.5 | 0, 4.5 | 0 | 0, 0 | 1.4 | 0, 4.1 | 0.7 | 0, 1.7 |
Abbreviation: CI, confidence interval.
Detection of urinary acetaminophen and/or ibuprofen metabolites matched with self-reported use of acetaminophen and/or ibuprofen.
Detection of urinary acetaminophen and/or ibuprofen metabolites but no reported use of acetaminophen and/or ibuprofen.
Indicates concordance for the other visit.
Reported use of acetaminophen and/or ibuprofen but no detection of urinary acetaminophen and/or ibuprofen metabolites.
Underdetection of urinary acetaminophen and/or ibuprofen metabolites at one visit and underreporting of acetaminophen and/or ibuprofen use at the other visit.