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Bim is not required for negative selection to UbA. (A) CD4 by CD8 profile of Vα2+ thymocytes from OT-I→B6 (n = 7), OT-I→Act-mOVA (n = 3), OT-I Bim−/−→B6 (n = 8), and OT-I Bim−/−→Act-mOVA (n = 3). (B) Number of Vα2+ DP and Vα2+ CD8+ thymocytes recovered from thymi of indicated strains. Data depict means and are representative of the indicated number of samples. *P < 0.05, **P ≤ 0.01.
