Fig. 3.

(A) Stack radio-TLC chromatogram of the crude [¹⁸F]TAG (green trace), crude [¹⁸F]FDG (blue trace), and purified [¹⁸F]FDG (red trace) from a typical on-chip synthesis. The radio-TLC profile of the purified [¹⁸F]FDG showed > 99% chemical purity after passing through the custom made cartridge shown in (B), with 88% purification efficiency. (B) A schematic diagram of the custom made cartridge comprised of ion retardation, cation exchange, neutral alumina and C-18 resins packed within a 760 μm diameter perfluoroalkoxy tube.