Table 3.

One-Pot, click/OACC esterification.

entry	scaffold	azide	acid	yield (%)
1	18	P	21	48
2	18	M	22	52
3	18	M	23	47
4	18	P	23	60
5	19	M	22	40
6	19	M	23	42
7	19	M	24	43

^aReaction conditions: Isothiazole 1,1-dioxide (40 mg, 1 equiv.), acid (1.2 equiv.), azide (2 equiv.), OACC (1.5 equiv.), CuI (30 mol%), DBU (10 mol%), dry CH₂Cl₂ (0.2 M), 50 °C, 12 h.

^bIsolated yields after standard column chromatography (EtOAc, R_f = 0.3–0.6).