Table 1. Genera frequencies in the Twins Clusters.
Rank | Genus | Diff. | C. Diff. | |||||
1 | Bacteroides | 17.5 | 5-6.8-8 | 21-22.6-25 | 35-38.8-43 | 7-8.3-11 | 46.3 | 29.2 |
2 | Unknown | 30.8 | 26-29.1-33 | 31-33.6-37 | 20-22.4-25 | 39-45.2-53 | 27.2 | 46.4 |
3 | Faecalibacter. | 10.0 | 12-13.8-16 | 8-8.8-10 | 12-13.8-16 | 3-4.0-5 | 14.9 | 55.8 |
4 | Prevotella | 0.60 | 4.2-5.18-6.3 | 0.2-0.22-0.3 | 0.1-0.14-0.2 | 0.2-0.40-0.7 | 5.6 | 59.4 |
5 | Alistipes | 2.33 | 1.5-1.86-2.4 | 3.5-4.02-4.7 | 1.4-1.66-2.0 | 0.7-0.99-1.4 | 4.2 | 62.0 |
6 | Dorea | 2.71 | 2.7-3.32-4.1 | 1.2-1.49-1.8 | 1.4-1.73-2.1 | 3.1-4.05-5.3 | 4.1 | 64.6 |
7 | Ruminococcus | 2.05 | 1.9-2.36-3.0 | 3.1-3.57-4.2 | 0.8-0.95-1.2 | 0.6-0.92-1.4 | 4.1 | 67.2 |
8 | Oscillibacter | 2.56 | 2.3-2.84-3.5 | 3.4-3.96-4.6 | 1.3-1.59-1.9 | 0.9-1.20-1.7 | 4.0 | 69.7 |
9 | Roseburia | 4.13 | 3.0-3.63-4.5 | 2.0-2.32-2.8 | 3.9-4.47-5.2 | 4.2-5.40-6.9 | 3.9 | 72.2 |
10 | Subdoligran. | 2.84 | 2.8-3.40-4.2 | 2.6-3.04-3.6 | 1.6-1.91-2.3 | 1.2-1.62-2.3 | 2.9 | 74.0 |
11 | Collinsella | 1.37 | 1.8-2.32-2.9 | 0.5-0.66-0.8 | 0.5-0.67-0.9 | 1.3-1.76-2.5 | 2.7 | 75.8 |
12 | Eubacterium | 1.03 | 1.9-2.47-3.1 | 0.3-0.40-0.5 | 0.4-0.52-0.7 | 0.8-1.16-1.6 | 2.7 | 77.5 |
13 | Hespellia | 1.04 | 0.4-0.54-0.8 | 0.5-0.65-0.8 | 0.5-0.69-0.9 | 1.4-1.95-2.6 | 2.1 | 78.8 |
14 | Coprococcus | 2.37 | 2.3-2.84-3.5 | 1.6-1.90-2.3 | 1.1-1.32-1.6 | 1.7-2.31-3.1 | 2.1 | 80.1 |
15 | Streptococcus | 1.12 | 0.9-1.21-1.6 | 0.4-0.57-0.7 | 0.5-0.62-0.8 | 1.2-1.65-2.2 | 1.7 | 81.2 |
16 | Coprobacillus | 1.13 | 0.6-0.77-1.1 | 0.8-0.95-1.2 | 0.5-0.59-0.8 | 1.1-1.58-2.2 | 1.5 | 82.2 |
17 | Catenibacterium | 0.35 | 0.8-1.09-1.5 | 0.1-0.09-0.2 | 0.1-0.15-0.2 | 0.2-0.30-0.6 | 1.2 | 82.9 |
18 | Eggerthella | 0.47 | 0.1-0.24-0.4 | 0.2-0.30-0.4 | 0.2-0.22-0.3 | 0.7-1.00-1.4 | 1.2 | 83.7 |
19 | Clostridium | 0.74 | 0.5-0.68-0.9 | 0.3-0.42-0.6 | 0.3-0.39-0.5 | 0.7-1.03-1.5 | 1.0 | 84.3 |
20 | Anaerotruncus | 1.02 | 0.8-1.07-1.4 | 0.7-0.85-1.1 | 0.4-0.52-0.7 | 0.5-0.76-1.1 | 1.0 | 84.9 |
21 | Odoribacter | 0.67 | 0.6-0.77-1.0 | 0.5-0.62-0.8 | 0.2-0.32-0.4 | 0.1-0.21-0.4 | 1.0 | 85.6 |
22 | Barnesiella | 0.56 | 0.5-0.71-1.0 | 0.5-0.60-0.8 | 0.2-0.22-0.3 | 0.1-0.13-0.3 | 1.0 | 86.2 |
23 | Megasphaera | 0.38 | 0.5-0.68-1.0 | 0.1-0.11-0.2 | 0.1-0.20-0.3 | 0.3-0.54-0.9 | 0.9 | 86.7 |
24 | Paraprevotella | 0.29 | 0.5-0.71-1.0 | 0.1-0.11-0.2 | 0.1-0.10-0.2 | 0.1-0.18-0.4 | 0.9 | 87.3 |
25 | Lactobacillus | 0.29 | 0.4-0.60-0.9 | 0.1-0.12-0.2 | 0.0-0.08-0.1 | 0.2-0.40-0.7 | 0.8 | 87.8 |
26 | Butyricimonas | 0.42 | 0.4-0.58-0.8 | 0.2-0.30-0.4 | 0.1-0.20-0.3 | 0.1-0.13-0.3 | 0.8 | 88.3 |
27 | Butyricicoccus | 0.87 | 0.6-0.79-1.1 | 0.4-0.47-0.6 | 0.5-0.60-0.8 | 0.6-0.84-1.2 | 0.8 | 88.8 |
28 | Lactonifactor | 0.63 | 0.5-0.65-0.9 | 0.3-0.35-0.5 | 0.3-0.34-0.5 | 0.6-0.81-1.2 | 0.8 | 89.3 |
29 | Parabacteroides | 0.77 | 0.4-0.59-0.8 | 0.5-0.64-0.8 | 0.3-0.40-0.5 | 0.5-0.68-1.0 | 0.8 | 89.8 |
30 | Dialister | 0.57 | 0.3-0.49-0.7 | 0.2-0.27-0.4 | 0.3-0.42-0.6 | 0.5-0.78-1.2 | 0.7 | 90.2 |
Percentage relative abundance of the first 30 out of 131 genera in the estimate of the mean of the reference single Dirichlet component, , and the four Dirichlet mixture components, fitted to the Twins data. For the mixture components the upper and lower 95% credible intervals are also given in the format (lower-MPE-upper). These are calculated as the maximum posterior estimate minus/plus two standard deviations as calculated from the inverse Hessian. Genera are ranked in order of their contribution to the total mean difference of 158%, split 34%, 26%, 51% and 47% across components, and the cumulative fraction of this difference accounted for given in the last column in the table.