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. 2012 Feb 3;7(2):e30126. doi: 10.1371/journal.pone.0030126

Table 3. Genera frequencies in the IBD phenotypes.

Rank Genus Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Diff. C. Diff.
1 Unknown 27.8 24-28.4-34 26-33.4-44 14-21.1-33 27-34.7-44 19.8 18.9
2 Bacteroides 27.2 24-28.7-35 22-28.7-38 12-19.6-31 26-32.5-41 15.9 34.1
3 Faecalibacter. 3.61 3.3-4.36-5.8 3.6-5.39-8.0 0.7-1.52-3.4 3.1-4.46-6.4 5.5 39.4
4 Escherichia/Shigella 0.93 0.3-0.58-1.0 0.2-0.50-1.1 2.1-3.85-7.0 0.2-0.41-0.8 4.2 43.4
5 Parabacteroides 3.49 2.3-3.19-4.3 1.9-3.07-4.9 2.6-4.77-8.6 1.5-2.31-3.6 3.2 46.5
6 Sutterella 1.00 0.6-0.95-1.5 0.2-0.49-1.1 1.3-2.63-5.3 0.1-0.30-0.7 2.9 49.2
7 Alistipes 3.61 3.3-4.41-5.9 2.4-3.79-6.0 1.3-2.56-5.1 1.9-2.92-4.4 2.7 51.8
8 Prevotella 0.77 0.5-0.79-1.3 0.0-0.15-0.6 0.9-1.98-4.4 0.2-0.36-0.8 2.3 54.0
9 Dorea 1.98 1.2-1.65-2.3 0.9-1.48-2.5 1.4-2.70-5.2 0.8-1.29-2.1 2.2 56.2
10 Klebsiella 0.47 0.2-0.34-0.6 0.1-0.21-0.7 0.9-1.95-4.4 0.1-0.16-0.5 2.2 58.2
11 Bifidobacterium 1.91 1.1-1.59-2.3 1.5-2.48-4.1 1.2-2.32-4.7 0.7-1.14-1.9 2.1 60.2
12 Barnesiella 1.65 1.3-1.88-2.7 0.8-1.47-2.6 0.1-0.49-1.9 0.8-1.30-2.2 1.9 62.1
13 Oscillibacter 2.49 2.0-2.75-3.8 1.4-2.31-3.8 0.7-1.60-3.6 1.3-1.97-3.1 1.9 63.9
14 Streptococcus 0.67 0.3-0.44-0.8 0.2-0.44-1.0 0.8-1.76-3.7 0.2-0.37-0.8 1.8 65.6
15 Coprococcus 1.73 0.9-1.37-2.0 0.7-1.20-2.1 1.2-2.41-4.7 0.9-1.46-2.4 1.8 67.4
16 Veillonella 0.17 0.0-0.03-0.2 0.0-0.00-0.0 0.7-1.59-3.6 0.0-0.09-0.4 1.8 69.1
17 Subdoligranulum 2.33 1.8-2.47-3.4 1.2-1.93-3.2 0.7-1.62-3.6 1.2-1.86-3.0 1.7 70.7
18 Paraprevotella 0.55 0.4-0.60-1.0 0.0-0.14-0.5 0.6-1.36-3.3 0.1-0.21-0.6 1.6 72.3
19 Acidaminococcus 0.19 0.0-0.06-0.3 0.0-0.07-0.5 0.6-1.35-3.3 0.0-0.09-0.4 1.5 73.7
20 Lactobacillus 0.20 0.0-0.13-0.3 0.0-0.13-0.5 0.5-1.27-3.1 0.0-0.00-0.0 1.4 75.1
21 Ruminococcus 1.47 1.0-1.40-2.0 0.7-1.29-2.3 0.4-1.01-2.7 0.5-0.94-1.6 1.2 76.3
22 Lactonifactor 0.11 0.0-0.06-0.2 0.0-0.00-0.0 0.4-1.01-2.7 0.0-0.00-0.0 1.2 77.4
23 Odoribacter 1.11 0.7-1.04-1.5 0.4-0.73-1.4 0.3-0.93-2.5 0.4-0.69-1.2 1.0 78.4
24 Butyricicoccus 1.01 0.6-0.92-1.4 0.3-0.53-1.1 0.3-0.93-2.5 0.4-0.66-1.1 1.0 79.3
25 Fusobacterium 0.09 0.0-0.06-0.3 0.0-0.00-0.0 0.3-0.80-2.5 0.0-0.00-0.0 0.9 80.2

Percentage relative abundance of the first 25 out of 95 genera in the estimate of the mean of the reference single Dirichlet component, Inline graphic, fitted to all IBD individuals, and the four single component Dirichlet models, fitted to healthy (Inline graphic), colonic Crohn's disease (CCD - Inline graphic), ileal Crohn's disease (ICD - Inline graphic), and ulcerative colitis (UC - Inline graphic) phenotypes. For the mixture components the upper and lower 95% credible intervals are also given in the format (lower-MPE-upper). These are calculated as the maximum log posterior estimate minus/plus two standard deviations as calculated from the inverse Hessian. Genera are ranked in order of their contribution to the total difference of 104% to the reference split 9%, 20%, 48%, 27% across phenotypes, and the cumulative fraction of this difference accounted for given in the last column in the table.