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. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Hepatology. 2012 Apr;55(4):1182–1192. doi: 10.1002/hep.24735

Table 1. Representation of major functionally annotated groups in differentially expressed gene lists in NHB donor liver versus HB donor liver.

Gene ontology groups NHB donor liver 16h NHB donor liver 30h
Number Upregulated genes (%) Number Downregulated genes (%) Number Upregulated genes (%) Number Downregulated genes (%)
Cellular process 195 (61%)
Metabolic process 27(43%) 136 (48%)
Cellular metabolic process 14 (45%) 26 (41%) 143 (44%)
Primary metabolic process 14 (45%) 136 (42%)
Transport 10 (32%) 59 (18%) 11 (17%)
Cellular component organization and biogenesis 10 (32%) 55 (17%)
Localization 10 (32%) 68 (21%)
Biological regulation 10 (32%) 21 (33%) 17 (27%)
Regulation of biological process 9 (29%) 19 (30%) 15 (24%)
Developmental process 8 (26%) 13 (21%) 12 (19%)
Macromolecule metabolic process 9 (29%) 23 (37%) 103 (32%)
Establishment of localization 10 (32%) 61 (19%) 11 (17%)
Protein metabolic process 9 (29%) 65 (20%)
Cellular protein metabolic process 64 (20%)
Regulation of cellular process 9 (29%) 16 (25%)
Regulation of cellular metabolic process 13 (21%)
Biosynthetic process 6 (19%) 46 (14%)
Response to stress 5 (16%) 7 (11%) 26 (8%) 8 (13%)
Negative regulation of biological process 5 (16%)
Immune system process 5 (16%)
Secretion 4 (13%)
Cell death 4 (13%) 23 (7%)
Leukocyte activation (10%)
Multicellular organismal development (10%) 11 (17%)
Biopolymer metabolic process 17 (27%)
Regulation of metabolic process 14 (22%)
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 13 (21%)
Transcription, DNA-dependent 11 (17%)
Transcription 11 (17%)
Regulation of transcription, DNA-dependent 11 (17%)
RNA biosynthetic process 11 (17%)
Regulation of gene expression 11 (17%)
RNA metabolic process 11 (17%)
Regulation of transcription 11 (17%)
Intracellular signaling cascade 10 (16%) 31 (10%)