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. Author manuscript; available in PMC: 2013 Mar 1.

Published in final edited form as: Pharmacol Biochem Behav. 2011 Dec 14;101(1):69–76. doi: 10.1016/j.pbb.2011.12.002

Fig. 3 — Effect of antagonist pretreatment on LSD-elicited head bobs. a Rabbits were pretreated with ketanserin (3 or 10µmol/kg), ritanserin (0.67µmol/kg), SB206553 (1µmol/kg), or SCH23390 (0.05µmol/kg) before administration of LSD (30nmol/kg). LSD-elicited head bobs are shown as the mean ± SEM. b Analysis of the behavioral time course of LSD-elicited head bobs following pretreatment with vehicle (H₂O) or ketanserin (3µmol/kg). LSD-elicited head bobs are shown in 10 minute bins. The first 5 minutes is not included in the analysis due to the large stress response immediately after injection. **p<0.001, ***p<0.0001, post-hoc Dunnett test, significantly different from vehicle pretreated group, n=4 to 18.

Fig. 3 — Effect of antagonist pretreatment on LSD-elicited head bobs. a Rabbits were pretreated with ketanserin (3 or 10µmol/kg), ritanserin (0.67µmol/kg), SB206553 (1µmol/kg), or SCH23390 (0.05µmol/kg) before administration of LSD (30nmol/kg). LSD-elicited head bobs are shown as the mean ± SEM. b Analysis of the behavioral time course of LSD-elicited head bobs following pretreatment with vehicle (H₂O) or ketanserin (3µmol/kg). LSD-elicited head bobs are shown in 10 minute bins. The first 5 minutes is not included in the analysis due to the large stress response immediately after injection. **p<0.001, ***p<0.0001, post-hoc Dunnett test, significantly different from vehicle pretreated group, n=4 to 18.