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. 2012 Jan 1;11(1):19–25. doi: 10.4161/cc.11.1.18633

Figure 1.

Figure 1

TIN2-C and FN-tankyrase 1 induce telomere lengthening by different mechanisms. (A) Schematic diagrams of TRF1 and its binding partners, tankyrase 1 (TNKS1) and TIN2. (B) Graphical representation of telomere length changes in stable HTC75 cell lines overexpressing TIN2-C, FNtankyrase 1 (TNKS1), or vector. (C) Immunoblot analysis of the stable lines probed with antibodies against TNKS1, TIN2, TRF1 or TRF2. (D) Immunofluorescence analysis of transiently transfected HeLaI.2.11 cells costained with antibodies against Flag (green) and TRF1 (red) and DAPI (blue).