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RRD-251 inhibits Rb-Raf-1 interaction in AoSMCs. (A and B) Treatment with TNFα or PDGF in the presence of RRD-251 inhibits Raf-1 levels in AoSMCs (A) and A10s (B). (C) TNFα and PDGF treatment induced Rb-Raf-1 binding in AoSMCs. (D) RRD-251 inhibits TNFα-induced Rb-Raf-1 interaction.
