Table 1.
Fold Change in the Expression Level of Cell Cycle Genes in EPCs After TRPC1 Knockdown
| Symbol | GeneBank | Gene name | Fold change |
|---|---|---|---|
| Upregulated | |||
| Ak1 | NM_024349 | Adenylate kinase 1 | 3.67 |
| Brca2 | NM_031542 | Breast cancer 2 | 2.22 |
| Camk2b | NM_021739 | Calcium/calmodulin-dependent protein kinase II beta | 3.23 |
| Cdkn1a | NM_080782 | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 3.44 |
| Ddit3 | NM_024134 | DNA-damage inducible transcript 3 | 6.96 |
| Inha | NM_012590 | Inhibin alpha | 5.52 |
| Slfn1 | XM_001068751 | Schlafen 1 | 9.42 |
| Mdm2 | XM_235169 | Mdm2 p53 binding protein homolog (mouse) | 2.46 |
| Prm1 | NM_001002850 | Protamine 1 | 3.02 |
| Downregulated | |||
| Bcl2 | NM_016993 | B-cell CLL/lymphoma 2 | 2.72 |
| Mki67 | XM_225460 | Antigen identified by monoclonal antibody Ki-67 | 2.24 |
| Pmp22 | NM_017037 | Peripheral myelin protein 22 | 2.27 |
| Ppp2r3a | XM_576459 | Protein phosphatase 2 (formerly 2A), regulatory subunit B′′, alpha | 2.99 |
Three separate experiments were performed in triplicate. P<0.05 compared with siRNA-control.