Comparative effects of glibenclamide and riluzole on lesion size. A: Representative H&E-stained sections of spinal cords at the epicenter of injury, 6 weeks after SCI, from rats treated with either riluzole or glibenclamide, as indicated. B,C: Lesion volumes (B) and lesion areas as a function of distance from the epicenter (C), 6 weeks after SCI, in rats treated with either riluzole or glibenclamide (GLIB), as indicated, beginning 3 h after impact and continuing for 1 week; 13 rats per group.