Figure 5.

Normal small intestinal epithelial cells are not radiosensitized by AZD7762 and/or olaparib. CCL-241 cells were treated as illustrated (Fig. 1D). Data are from a single representative experiment (A) or are the mean radiation enhancement ratio ± SE from n = 3 experiments (B). Statistically significant differences are indicated vs. control (*p < 0.05; there were no significant differences in the radiation enhancement ratios). (C) At the end of treatment, cells were analyzed by immunoblotting for the indicated proteins. Data are from a single representative experiment.