Figure 2.

Multiple blocks in the endolysosomal pathway elevate Yki activity. α-β-gal staining of larval imaginal wing discs in which the ex-lacZ SWH-reporter has been placed in the background of (A) en, (B) en > AP-2σ-IR (C) en > Rab5^DN (D) en > syx7-IR and (E) en > vps25-IR animals. Tangential and lateral sections are shown for each genotype. Lateral sections were obtained from the dorsal-ventral margin of the wing epithelium as indicated by the line in (A). Posterior compartment is to the right of the dotted line.