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. 2011 Dec 1;10(23):4119–4127. doi: 10.4161/cc.10.23.18287

Figure 4.

Figure 4

Knockdown of C1qbp reduces proliferation in MDA-MB-231 breast cancer cells. (A) MDA-MB-231 cells were stably transfected with either a control shRNA (Con) or one of 3 different C1qbp-specific shRNAs and then protein gel blotted for C1qbp. GAPDH was used as a loading control. (B) Quantification of the efficiency of C1qbp knockdown in the MDA-MB-231 shRNA cell lines. (C) Each of the MDA-MB-231 shRNA cell lines was plated at an equal density, and the increase in cell numbers after 48 hrs measured by bis-benzamide staining of the nuclei. (D) ATP levels in the control and C1qbp shRNA MDA-MB-231 cell lines. The results shown are representative of 3 and 4 independent experiments performed in duplicate. Error bars indicate SEM and *p < 0.05 vs. Con sh.