Fig. 2.
Biochemical analysis of lipid metabolism in skeletal muscle of male mice. Mixed skeletal muscle was isolated (gastrocnemius and soleus) from overnight-fasted 5 to 7 months old male mice (white bars, Cc2+/+; black bars, Cc2−/− all panels). a mRNA expression of genes involved in fatty acid uptake and oxidation was determined by semi-quantitative real-time PCR and normalised to Gapdh. b FATP1 abundance by western blot analysis, using α-FATP1 antibody to immunoblot (Ib) and α-actin antibody to reprobe (reIb) and normalise against the amount of protein loaded. c Ex vivo palmitate oxidation. d triacylglycerol content. Values are expressed as mean±SEM; n=4–8 per group; *p<0.05 vs Cc2+/+