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. Author manuscript; available in PMC: 2012 Feb 5.
Published in final edited form as: Brain. 2011 May 15;134(Pt 6):1839–1852. doi: 10.1093/brain/awr076

Figure 1.

Figure 1

Simplified and virtual pedigree, as used for the linkage study, including Families A and B. The gender of the family members is not shown for privacy. Filled and crossed out symbols indicate affected and deceased persons, respectively. Individuals denominated with a ‘B’ have been added to the pedigree for linkage studies, because they exhibit the same phenotype as individuals of Family A, are excluded for mutations in the known Charcot-Marie-Tooth disease type 1 genes, and originate from the same small village. For linkage analyses, samples from Patients B5, B9, A11, A14, A15, A16, A17, A18, A19, A20, A21, A22 and A23 were genotyped using the Affymetrix GeneChip® Human Mapping 10K XbaI 142 2.0 array. Individuals B5, B9, A11, A17 and A23 were later genotyped using the high-density Affymetrix GeneChip® Human Mapping 6.0 array for high-resolution confirmation of a common haplotype in Families A and B and fine mapping of the candidate region.