Table 3.

 Estimates for ARMA (1,1) model*: symptom severity scores over time (65 541 observations in 2560 patients from 364 clinicians)

	Parameter estimate, P value	Interactions with time, P value
Management
Prescribed antibiotics	0.05, 0.26	−0.01, <0.01
Network
Antwerp	0.05, 0.52	-0.01, 0.03
Balatonfured	-0.27, <0.001	-0.01, 0.02
Barcelona	-0.07, 0.32	0.00, 0.84
Bratislava	-0.04, 0.50	-0.00, 0.29
Cardiff	0.09, 0.17	0.01, 0.02
Helsinki	0.03, 0.72	0.00, 0.62
Jonkoping	0.02, 0.78	0.01, <0.001
Lodz	-0.05, 0.38	-0.01, 0.07
Mataro	0.28, <0.001	-0.02, <0.001
Milan	-0.13, 0.08	0.01, <0.01
Rotenberg	0.02, 0.77	0.00, 0.98
Southampton	0.01, 0.90	0.01, 0.08
Tromso	0.11, 0.14	0.00, 0.42
Utrecht	-0.05, 0.52	0.00, 0.88

*Model controls for clinician recorded symptom scores and clinical presentation as well as allowing recovery trajectory to follow cubic polynomial.