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(A) Regional muscle flow during exercise and (B) oxygen saturation in blood supplied to exercising muscle. Note that in diabetics with reasonable control increase in flow is not able to contain desaturation. Diabetics with poor control show limited capacity to augment flow and run up a steeper oxygen debt with a late attempt at correction which could be due to local factors over-riding systemic vascular tone. HbA1c, glycosylated haemoglobin.
