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. Author manuscript; available in PMC: 2012 Feb 6.
Published in final edited form as: Methods Mol Biol. 2009;566:69–83. doi: 10.1007/978-1-59745-562-6_5

Figure 2.

Figure 2

Representative Western blot analysis of proteins isolated from the nucleus accumbens of monkeys following eighteen months of cocaine self-administration compared to controls. Protein was isolated from membrane fractions and levels of ionotropic glutamate receptor subunit proteins GluR1, GluR2/3 and GluR5 were evaluated (5 μg) following separation on 10% SDS-PAGE. Data are expressed as mean (± S.E.M.) of the percent of control values per amount of protein loaded. Asterisks indicate a significant difference (P<0.05). B. Representative bands from two cocaine self-administration monkeys (+) and two control subjects (−) for each subunit are shown. Reprinted with permission from the Journal of Neurochemistry.