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. Author manuscript; available in PMC: 2012 Feb 6.
Published in final edited form as: Brain Res. 2010 Jan 4;1318:144–154. doi: 10.1016/j.brainres.2009.12.050

Figure 3.

Figure 3

Effect of chronic self-administration by cynomolgus macaques on NMDA subunit expression in OFC. Ethanol self-administration did not affect NMDA receptor subunit mRNA expression in this region (A). A significant interaction was observed for GRIN1 splice variant expression, with post hoc analysis revealing a significantly decreased GRIN1-1 expression and increased GRIN1-2 expression in the ethanol group (B). Black bar – control subjects, gray bar – ethanol subjects. Asterisks indicate a significant difference compared to control subjects (P<0.05).