Table 1.
Effect of renal ischemia and reperfusion on renal function parameters, local CXCL1 production, and local and remote neutrophil accumulation. Urinary creatinine (mg/dL), serum creatinine (mg/dL), serum osmolality (mOsm/Kg H2O), urinary osmolality (mOsm/Kg H2O), serum CXCL1 (pl/mL serum), and renal and pulmonary neutrophils (relative units).
| Control | I/R | n | P | |
|---|---|---|---|---|
| Urinary creatinine (mg/dL) | 700 ± 5.1 | 170 ± 1.2* | 6 | 0.001 |
| Serum creatinine (mg/dL) | 0.29 ± 0.1 | 5.34 ± 1.2* | 4 | 0.016 |
| Serum osmolality (mOsm/Kg H2O) | 317 ± 10.4 | 360 ± 17.8* | 6 | 0.006 |
| Urinary osmolality (mOsm/Kg H2O) | 3996 ± 340 | 905 ± 69* | 6 | 0.06 |
| Serum CXCL1/KC (pg/mL) | 94 ± 70 | 940 ± 164* | 6 | 0.008 |
| Renal neutrophils (relative units) | 0.26 ± 0.13 | 5.3 ± 1.2* | 4 | 0.016 |
| Lung neutrophils (relative Units) | 2.2 ± 0.5 | 5.6 ± 0.5* | 5 | 0.0015 |