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. Author manuscript; available in PMC: 2012 Feb 6.
Published in final edited form as: Drug Alcohol Depend. 2007 Jul 23;91(2-3):269–278. doi: 10.1016/j.drugalcdep.2007.06.007

Figure 1.

Figure 1

Effect of atazanavir on the time versus concentration curves of buprenorphine and its metabolites. Shown are mean concentrations at each time point in study participants taking sublingual buprenorphine/ naloxone (16/4 mg daily) alone (■) and study participants taking the same dose of buprenorphine/naloxone in combination with 400 mg of atazanavir daily (●). The panels show the mean concentrations of (a) buprenorphine, (b) norbuprenorphine, (c) buprenorphine-3-glucuronide and (d) norbuprenorphine-3-glucuronide.