Table 2.
Characteristics of hepatic arterial embolization for NET metastases.
Indications | |
Hepatic metastases of NET | |
Nonoperative candidates | |
Symptomatic and asymptomatic tumors | |
| |
Contraindications | |
Main portal vein thrombosis | |
Bilirubin greater than 2-3 mg/dL | |
Hepatic tumor burden greater than 75% | |
Contraindications to angiography | |
| |
Outcomes | |
Mortality 0–6% | |
Median OS 25–56 months | |
5-yr survival 13–28% | |
| |
Common chemotherapeutic agents | |
None (bland embolization) | |
Doxorubicin | |
Mitomycin C | |
Cisplatin | |
| |
Most frequent complications | |
Postembolization syndrome | |
Hepatic abscess | |
Hepatic failure | |
Cholecystitis | |
Pancreatitis | |
| |
Indications for repeat embolization | |
Increase in tumor size or tumor enhancement | |
Progression of symptoms |