Antibody responses to asexual blood-stage whole P. falciparum parasites (A), P. falciparum MSP-119 (PfMSP-119) (B), P. falciparum AMA-1 (PfAMA-1) (C), and P. falciparum EBA-175 (PfEBA-175) (D) in children up to 2 years of age. For IFAT data (A), IgG levels (y axes in log scale) are expressed as endpoint titers. For ELISA data (B to D), IgG (left) and IgM (right) levels are expressed as normalized OD values (y axes, percentages). In the weighted scatter plots, the area of the symbol is proportional to the number of observations. Geometric mean IgG titers and 95% confidence intervals are indicated by horizontal continuous and dashed lines, respectively. Red symbols correspond to IgG levels in children with previous or present infection.