Fig 2.
Highly pathogenic clade 2.2 challenge. Vaccinated BALB/c mice (5 mice/group) were infected with 5 × 103 PFU of the highly pathogenic clade 2.2 H5N1 virus A/Whooper Swan/Mongolia/244/2005 (WS/05). (A and B) Mice were monitored daily for weight loss (A) and sickness (B). (C and D) Vaccinated Fitch ferrets (6 ferrets/group) were infected with 1 × 106 PFU of the highly pathogenic clade 2.2 WS/05 virus. Ferrets were monitored daily for weight loss (C) and sickness (D). Values are the means and the standard errors of the mean (SEM) for each group.