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. 2012 Jan 12;106(3):496–507. doi: 10.1038/bjc.2011.577

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Copyright © 2012 Cancer Research UK

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

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Computed tomography imaging of an orthotopic bladder tumour model during treatment with Oncovex^GALV/CD + 5-FC. Intravesical treatment of implanted tumours was carried out with virus (Oncovex^GALV/CD, 9e7 pfu) (or Control PBS) on days 6, 12, and 18. Prodrug 5-FC (12.5 mg ml^–1) was installed in the same manner on days 7, 8, 13, 14, 19, and 20 and the animals were killed on day 29. During the experiment, computed tomography imaging was carried out on days 5, 11, 15, 22, and 29.