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. 2011 Dec 20;106(3):475–481. doi: 10.1038/bjc.2011.564

Table 1. FLT3 kinase-inhibitory activity of BPR1J-097.

In vitro kinase inhibition IC50, nM
BPR1J-097 11±7
ABT-869 17±7
Sorafenib 44±9
PKC412 37±5

Abbreviation: FLT3=Fms-like tyrosine kinase 3.

Each IC50 determination was performed with eight concentrations by kinase-Glo assay. Data represent mean±s.d. from three different experiments.