Table 2. Relative risk for lung cancer by selected characteristics at reference datea.
Lung cancer
|
Controls
|
|||||
---|---|---|---|---|---|---|
N | % | N | % | ORb (95% CI) | Smoking-adjusted ORc (95% CI) | |
Overall | 68 | 337 | ||||
Smoking status | ||||||
Never | 2 | 3.8 | 71 | 27.1 | 1 | |
Former | 6 | 11.5 | 63 | 24.0 | 3.22 (0.63–16.6) | |
Current | 44 | 84.6 | 128 | 48.9 | 14.4 (3.36–62.1) | |
Unknown | 16 | 75 | ||||
Pack-yearsd | ||||||
<30 | 16 | 36.4 | 62 | 50.8 | 11.5 (2.42–54.6) | |
⩾30 | 28 | 63.6 | 60 | 49.2 | 15.9 (3.67–69.1) | |
Unknown | 0 | 6 | ||||
History of cART use | ||||||
Never | 18 | 26.5 | 77 | 22.8 | 1 | 1 |
Ever | 50 | 73.5 | 260 | 77.2 | 0.67 (0.29–1.52) | 0.73 (0.31–1.70) |
History of AIDS-defining disease | ||||||
No | 54 | 79.4 | 229 | 68.0 | 1 | 1 |
Yes, without pulmonary diseasee | 8 | 11.8 | 62 | 18.4 | 0.53 (0.24–1.18) | 0.60 (0.27–1.36) |
Yes, with pulmonary diseasee | 6 | 8.8 | 46 | 13.6 | 0.49 (0.19–1.28) | 0.62 (0.22–1.72) |
Nadir CD4+ cell count, cells per μl | ||||||
⩾200 | 31 | 45.6 | 142 | 42.4 | 1 | 1 |
50–199 | 26 | 38.2 | 124 | 37.0 | 0.96 (0.54–1.71) | 1.07 (0.57–2.02) |
<50 | 11 | 16.2 | 69 | 20.6 | 0.73 (0.34–1.55) | 0.87 (0.39–1.90) |
Unknown | 0 | 2 |
Abbreviations: cART=combined antiretroviral therapy; CI=confidence interval; OR=odds ratio.
See the ‘Materials and Methods’ section for definition of reference date.
Conditioned upon matching variables.
Conditioned upon matching variables and adjusted for smoking status (never/former, current with <30 pack-years, current with ⩾30 pack-years, unknown).
Current smokers only.
Includes recurrent bacterial pneumonia, pulmonary tuberculosis, or Pneumocystis carinii pneumonia.