Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jan 5;106(3):553–561. doi: 10.1038/bjc.2011.568

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2012 Cancer Research UK

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Ectopic expression of miR-200c in melanoma cells causes ZEB2 downregulation and E-cadherin upregulation. Expression was determined by qRT–PCR after transfection of A375 melanoma cells with miR-200c precursor, or a combination of miR-200c and miR-205 precursors (dark shading), or a scrambled control miRNA (intermediate shading); non-transfected negative control (light shading). Mean relative expression levels (±s.e.m.) from three independent experiments are shown (A) Expression of miR-200c relative to miR-92 and normalised to the mean of the negative control. (B) Expression of ZEB2 mRNA after transfection with miR-200c precursor relative to β-actin and normalised to the mean of the negative control. (C) Expression of ZEB2 mRNA after transfection with miR-200c and miR-205 precursors relative to β-actin. (D) Expression of E-cadherin mRNA after transfection with miR-200c precursor relative to β-actin. ^*P<0.05; ^***P<0.001.