Table 2.
Comparison of fatigue, plasma vitamin C levels, and oxidative stress between the two groups.
| Vitamin C Group (n = 70) |
Placebo Group (n = 71) |
p value‡ | |||||
|---|---|---|---|---|---|---|---|
| Baseline | 2 hours after intervention | 1 day after intervention | Baseline | 2 hours after intervention | 1 day after intervention | ||
| Fatigue right now* | 5.64 ± 2.02 | 5.10 ± 2.04 | 4.97 ± 2.33 | 5.54 ± 2.07 | 5.31 ± 2.00 | 5.66 ± 2.16 | 0.004 |
| Usual fatigue during the previous 24 hours | 5.59 ± 1.56 | - | 5.37 ± 2.06 | 5.77 ± 1.73 | - | 5.55 ± 1.79 | 0.870 |
| Worst fatigue during the previous 24 hours | 7.16 ± 1.83 | - | 6.47 ± 2.13 | 7.14 ± 1.77 | - | 6.82 ± 1.97 | 0.202 |
| Plasma vitamin C level (μg/ml) | 12.66 ± 6.50 | 267.90 ± 141.83 | - | 12.13 ± 4.99 | 12.52 ± 5.70 | - | < 0.001 |
| Oxidative stress (mmol/dl H2O2)† | 311.76 ± 74.15 | 184.46 ± 59.41 | 296.11 ± 64.37 | 310.89 ± 74.90 | 327.21 ± 78.80 | 303.72 ± 81.26 | < 0.001 |
*Fatigue was measured using a numeric rating scale, 0-10.
†Oxidative stress was measured using the Free Oxygen Radicals Test (FORT).
‡p value from ANCOVA.