Table 1.
Phosphorylated protein kinase | Amounts of phosphorylated protein kinase (pg/ml) | ||
---|---|---|---|
No stimulation | C. albicans stimulation (MOI = 15) | ||
No pre-treatment | AC-PAC pre-treatment | ||
AKT (Ser 473) | 614 ± 171 | 1184 ± 186* | 782 ± 110* |
AKT (Thr 308) | 60 ± 17 | 111 ± 29* | 113 ± 24 |
MEK1 (Ser 217/Ser 221) | 2072 ± 383 | 6359 ± 255* | 3596 ± 773† |
ERK1/2 (Thr 202/Tyr 204) | 67 ± 2 | 97 ± 8* | 41 ± 6† |
The data are the means ± SD of triplicate assays. *significantly higher compared to the unstimulated control (P < 0.05); †significantly lower compared to the untreated (AC-PACs) control (P < 0.05).