Figure 1. The progression of CAC over 3 years follow up (n = 466).

Filled bars designate CAC scores at follow up. Coronary artery calcification scores of 100–400, 400–999, and ≥1000 predict up to 4-, 7-, and 11-fold increases in future CVD risk, respectively, compared with patients with no detectable CAC. There was a significant increase in log Agatston score between baseline and follow up (2.25 vs 2.65, p<0.001), and 38.2% had progression of CAC as defined by an increase in >10 Agatston units.