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. 2012 Feb 6;7(2):e31066. doi: 10.1371/journal.pone.0031066

Figure 3. Intraperitoneal injection of BP180/CXVII-specific IgG induces blister formation in adult mice.

Figure 3

Skin lesions, including blisters, erosions, and crusts developed on the (A) ear, (B) front leg and (C) periocular area in a BALB/c mouse pre-sensitized with rabbit IgG and subsequently receiving, over a period of 10 days, 6 i.p. injections of IgG, each containing 15 mg of IgG, from a rabbit immunized against murine BP180/CXVII. (D, E, F) A control mouse pre-sensitized with rabbit IgG and challenged with the same dose of normal rabbit IgG showed no skin alterations.