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. 2012 Feb 6;7(2):e31066. doi: 10.1371/journal.pone.0031066

Figure 4. Subcutaneous injection of BP180/CXVII-specific IgG induces blister formation in adult mice.

Figure 4

Skin lesions, including blisters, erosions crusts, and alopecia developed in (A) BALB/c, (B) C57BL6, and (C) SJL-1 mice pre-sensitized with rabbit IgG and subsequently receiving, over a period of 10 days, 6 s.c. injections of IgG, each containing 15 mg of IgG, from a rabbit immunized against murine BP180/CXVII. (D) A control mouse pre-sensitized with rabbit IgG and challenged with the same dose of normal rabbit IgG showed no skin alterations.