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. 2012 Feb 6;7(2):e31066. doi: 10.1371/journal.pone.0031066

Figure 8. Neutrophil depletion partly inhibits skin blistering induced by BP180/CXVII-specific IgG in mice.

Figure 8

Mice pre-immunized with rabbit IgG and injected i.p. with BP180/CXVII-specific rabbit IgG were treated with (A) a Ly-6G-specific monoclonal or (B) a mock antibody as described in Materials and Methods (arrows). (C) Disease activity during the depletion of Ly-6G-positive cells is significantly reduced in the group of mice treated with Ly-6G-specific antibody (n = 5) compared with the group treated with mock antibody (n = 5; p<0.05). Data are shown as mean ± SD.