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. Author manuscript; available in PMC: 2013 Feb 15.
Published in final edited form as: J Immunol. 2012 Jan 16;188(4):1630–1637. doi: 10.4049/jimmunol.1101712

Fig. 3.

Fig. 3

Effect of Nrf2 activation on cytokine production in activated CD4+ cells. Magnetically-isolated CD4+ cells from Nrf2-null and wild-type mice were pretreated with vehicle (VH) or tBHQ for 30 min prior to activation with anti-CD3/anti-CD28. The cells were then cultured for 96 h after which the cell supernatants were harvested. Cytokine concentrations in the supernatants were quantified by multiplex suspension assay. * denotes p<0.05 as compared to wild-type control. ‡ represents a significant difference (p<0.05) between the wild-type and Nrf2-null genotypes.