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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Toxicol In Vitro. 2011 Dec 8;26(2):295–303. doi: 10.1016/j.tiv.2011.12.001

Figure 5. UFPs- and/or CSE- induced Egr-1 upregulation in MPMVEC from wild-type mice was abolished by pre-treatment of cells with SB203580 (A) and PD98059 (B).

Figure 5

2 × 105 cells were seeded into each well of 6-well plates. After overnight culture, cells were pre-treated with 5 μM or 10 μM of SB203580 (A), or 20 μM of PD98059 (B) for 3 h, then treated with UFPs and/or CSE for one hour. Total RNA was extracted and used for real-time PCR. Data are shown as mean ± SD of three experiments with three replicates in each experiment. * Significant difference as compared with the control (without any treatment), p < 0.05; # Significant difference as compared with UFPs alone or CSE alone treated group, p < 0.05; $ Significant difference as compared with those with UFPs and/or CSE treatment but without SB203580 or PD98059 pre-treatment, p < 0.05.