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. Author manuscript; available in PMC: 2013 Feb 23.
Published in final edited form as: Brain Res. 2011 Dec 29;1439:88–95. doi: 10.1016/j.brainres.2011.12.037

Figure 1. DETA NONOate added to neuronal culture media for the final 24 hours of Pb2+ exposure spontaneously releases NO and does not affect cell viability.

Figure 1

(A) DETA (10 μM) did not cause a loss in cell viability as assessed by the MTS assay. Cell death was only observed with the excitotoxic concentration (100 μM) of glutamate (Glu). Data are the mean ± SEM and are the result of 4 assays. (B) During the 24 hr treatment period DETA supplementation resulted in significantly elevated levels of NO2 confirming increased NO release. Data are the mean ± SEM and are the result of 3 assays. # = significance from all other treatments, * = significance from treatments without DETA.