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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Clin Immunol. 2011 Oct 19;142(2):160–166. doi: 10.1016/j.clim.2011.10.001

Figure 1. Immune complex deposition and mesangial cell proliferation in WASp deficient mice.

Figure 1

Biopsy specimens from WT controls and Was-KO mice were examined pathologically at different time points. PAS staining of A: WT (>12months) and B: Was-KO (<6months), C: Was-KO (6–12months), D: Was-KO (>12months). Immunofluorescence studies showed immune complex deposition in Was-KO mice. E: IgG, F: IgA, G: IgM, H: C3. Electron microscopic examinations showed mesangial and paramesangial deposits (I), and hump-like deposits (K) in Was-KO mice and no deposits in WT mice (J).