. Author manuscript; available in PMC: 2013 Mar 1.

Published in final edited form as: Biochim Biophys Acta. 2011 Dec 31;1818(3):869–876. doi: 10.1016/j.bbamem.2011.12.023

Table 4.

The effect of proline-to-alanine mutations on the permeabilizing ability of DesHDAP1 and DesHDAP3. Propidium iodide, a membrane impermeable DNA intercalator, can enter bacterial cells only after membrane disruption. Data is presented as the ratio of propidium iodide fluorescence at 617 nm 5 minutes after addition of 2 μM peptide to the fluorescence before peptide addition. Uncertainty is reported as standard deviation.

	F_5-/F₀
	Wildtype	Proline mutant
BF2	1.29 ± 0.1	-
Magainin	1.52 ± 0.2	-
DesHDAP1	1.12 ± 0.06	1.06 ± 0.05
DesHDAP3	1.13 ±0.08	1.57 ±0.4