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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Eur Neuropsychopharmacol. 2011 Sep 14;22(3):183–199. doi: 10.1016/j.euroneuro.2011.07.010

Table 3.

Co-morbidity measures by baseline QIDS-SR16

Measure Analyses
Baseline QIDS-SR16
Bonferroni Correction
Mild
N=81
Moderate
N=238
Severe
N=260
Very severe
N=67
Test statistic p-
value
Mild vs.
Moderate
Mild vs.
Severe
Mild vs.
Very
severe
Moderate
vs. Severe
Moderate
vs. Very
severe
Severe
vs. Very
severe

% % % %
PDSQ
  Agoraphobia 1.2 8.4 12.7 22.4 χ2(3)=19.60 0.0002 0.0246 0.0027 <.0001 0.1211 0.0015 0.0455
  Alcohol abuse 9.9 12.6 8.1 10.4 χ2(3)=2.75 0.4325
  Bulimia 2.5 10.1 16.2 14.9 χ2(3)=12.52 0.0058 0.0305 0.0013 0.0057 0.0460 0.2660 0.8063
  Drug abuse 2.5 3.8 6.2 11.9 p <0.01 0.0503
  Generalized anxiety 3.7 15.5 24.6 37.3 χ2(3)=32.45 <.0001 0.0054 <.0001 <.0001 0.0119 <.0001 0.0373
  Hypochondriasis 2.5 0.8 6.9 10.4 p <0.01 <.0001 0.2677 0.1792 0.0792 0.0006 0.0005 0.3330
  Obsessive-compulsive 8.6 11.3 12.3 17.9 χ2(3)=3.18 0.3645
  Panic disorder 2.5 6.3 11.2 28.4 χ2(3)=34.00 <.0001 0.2563 0.0176 <.0001 0.0567 <.0001 0.0004
  Post-traumatic stress disorder 4.9 8.8 15.4 23.9 χ2(3)=17.04 0.0007 0.2611 0.0143 0.0008 0.0257 0.0009 0.0998
  Social phobia 7.4 22.3 34.6 41.8 χ2(3)=33.21 <.0001 0.0029 <.0001 <.0001 0.0024 0.0014 0.2755
  Somatoform 1.7 5.4 4.5 p <0.01 0.0244 0.5756 0.0472 0.0905 0.0270 0.1813 1.0000
  Substance abuse 9.9 14.7 12.0 17.9 χ2(3)=2.86 0.4141
Number of psychiatric disorders χ2(12)=63.54 <.0001 0.0076 <.0001 <.0001 0.0016 <.0001 0.1749
  0 70.4 47.9 35.9 23.9
  1 18.5 27.7 23.2 25.4
  2 7.4 10.5 18.5 16.4
  3 2.5 7.6 8.9 10.4
  4+ 1.2 6.3 13.5 23.9

Note: Chi-square for continuous measures indicates Kruskal-Wallis test.

Bold indicates significant (p <.05 for uncorrected analyses, p <.0083 for after Bonferroni correction.

QIDS-SR16 categories: mild = 0–10, moderate = 11–15, severe = 16–20, very severe = 21–27.

Abbreviations: PDSQ, Psychiatric diagnostic screening questionnaire; QIDS-SR16, 16 item quick inventory of depressive symptomatology – self-rated; SCQ, Self-administered comorbidity questionnaire.