Table 1.
Predicted motifs and the associated transcription factors that bind and potentially influence expression of target genes at various time points.
| Time point(s) | Target genes | Motif | Motif Function | Transcription Factor(s) |
|---|---|---|---|---|
| 4h, 12h, 1d | Ccbp2 | STAT6 | Positive | STAT6 |
| Ccl2 | STAT5B | Positive | STAT5B | |
| STATx | Positive | STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6 | ||
| Ccl7 | STAT5A | Positive | STAT5A | |
| STAT6 | Positive | STAT6 | ||
| STATx | Positive | STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6 | ||
| Osmr | STAT5B | Positive | STAT5B | |
| STATx | Positive | STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6 | ||
| Socs3 | STATx | Positive | STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, STAT6 | |
| Stat3 | STAT6 | Positive | STAT6 | |
| Tnfrsf12a | STAT6 | Positive | STAT6 | |
| 12h | Cxcl13, Lox | LEF1 | Positive | LEF1 |
| 12h | Fgf23, Grem1 | GATA-2 | Negative | GATA2 |
| 2d, 4d, 6d, 8d | Fn, Lox, P4hb, Pcolce | CREB | Positive | CREB1, CREM, ATF1, ATF2, ATF3, ATF4, ATF7 |
| 4d | Mmp14, Pcolce | SMAD-4 | Positive | SMAD4 |
| 4d, 12d | Bglap, Col1a2, Sp7 | SREBP-1 | Positive | SREBP1 |