Figure 6. POH1 enhances RAW 264.7c4 differentiation.
RAW 264.7c4 cells were either mock transfected or transfected with wild type full length POH1, amino terminal portion of POH (amino acids 1-180) or full length C120S POH1. Cells were cultured in M-CSF and RANKL for 7 days. The number of multinuclear cells (greater than 2 nuclei/cell) was counted and the results of two experiments performed in triplicate are presented. *p≤0.05 and ***p≤0.0005 vs. mock transfected