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Schematic representation of the experimental paradigms. (A) Intrastriatal transplantation of NIR815 human mesenchymal stem cells in 6-OHDA-lesioned animals. (B) Intranasal infusion of NIR815 human mesenchymal stem cells in 6-OHDA-lesioned animals.
Note: See Materials and Methods section for detailed description.
Abbreviations: 6-OHDA, 6-hydroxydopamine; IS, intrastriatal; IN, intranasal; PBS, phosphate-buffered saline; hMSCs, human mesenchymal stem cells.
