Table 2.
Apparent permeability (Pe) of Fluoresbrite® particles (50 nm and 100 nm particle diameters) across a monolayer of human placental choriocarcinoma (BeWo) cells. Pe was calculated as described in the text, and the P values compare six replicates of each experiment
| Time point (h) | Pe (cm/s) | P-value | |
|---|---|---|---|
|
|
|||
| 50-nm particles | 100-nm particles | ||
| 2 | 3.8 ± 1.1 × 10−5 | 1.8 ± 0.7 × 10−5 | 0.003 |
| 4 | 3.6 ± 1.4 × 10−5 | 1.5 ± 1.0 × 10−5 | 0.013 |
| 6 | 4.4 ± 1.3 × 10−5 | 1.1 ± 0.8 × 10−5 | <0.001 |
| 12 | 4.2 ± 1.2 × 10−5 | 1.1 ± 0.9 × 10−5 | <0.001 |
| 24 | 3.9 ± 0.5 × 10−5 | 9.7 ± 9.4 × 10−6 | <0.001 |