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. Author manuscript; available in PMC: 2013 Feb 3.
Published in final edited form as: J Proteome Res. 2011 Dec 12;11(2):1163–1174. doi: 10.1021/pr2008972

Figure 6. Synaptic ribbon composition and function. We have depicted the ribbon based in large part on known interactions and localizations of its protein constituents.<.

Figure 6

br>Binding of Liprin and ERC1 and Erc216, Liprin and Cam KInase II44, Ribeye and Bassoon13, CtBP1 and Bassoon13, ERC1 and Piccolo15, ERC1 and Bassoon15 have been described. Piccolo binds Actin-Binding Protein1, which in turn binds Actin, while actin also binds Catenin33,48. We have placed ATP Synthase and PGAM5 speculatively in our proposed model. The right hand portion of the figure illustrates the hypothesis that CtBP isoforms create vesicles by fission of endocytosed membranous cisterns.