Human brain 1H NMR spectra measured via ultra-short-echo-time STEAM and MEGA-PRESS editing and their LCModel analysis. Left panel: in vivo STEAM spectrum (TE = 6 ms, TR = 5 s, NT = 160) and metabolite spectra fitted via LCModel which overlap with the Asc resonance at 3.73 ppm. Right panel: in vivo MEGA-PRESS homonuclear unedited spectrum (sum of ‘on’ and ‘off’ scans), in vivo edited spectrum (TE = 112 ms, TR = 5 s, NT = 512), and edited spectra of metabolites fitted via LCModel. Inset: sagittal MRI with the typical location of the volume of interest in the occipital lobe.